For Healthcare Professionals
*FDA Orange Book, March 2020.
†To be used for illustrative purposes only. Individual dose will vary by patient and condition.
‡Use language required by state: D.A.W. (dispense as written), B.M.N. (brand medically necessary), or D.N.S. (do not substitute).
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Texacort® (hydrocortisone) topical solution 2.5% is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Important Safety Information
Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.
- Systemic absorption of topical corticosteroids can cause reversible hypothalamic-pituitary-adrenocortical (HPA) axis suppression, manifestations of Cushing’s syndrome, hyperglycemia, and glycosuria in some patients.
- Conditions which augment systemic absorption include: application of the more potent steroids, use over large surface areas, prolonged use, or the addition of occlusive dressings. In these cases, patients should be evaluated periodically for HPA axis suppression using urine free cortisol and ACTH stimulation tests.
- If HPA axis suppression is noted, attempt to withdraw or decrease the frequency of the drug, or substitute a less potent steroid.
- Upon drug discontinuation, recovery of HPA axis function is generally prompt and complete; infrequently, signs and symptoms of steroid withdrawal may occur, requiring supplemental systemic corticosteroids.
- Children may absorb proportionally larger amounts of topical corticosteroids and thus be more susceptible to HPA axis suppression, Cushing’s syndrome, and intracranial hypertension. Limit topical corticosteroids to the least effective amount. Chronic corticosteroid therapy can interfere with growth and development in children.
- If irritation develops, discontinue use and institute appropriate therapy.
- In the presence of skin infections, an appropriate antimicrobial agent should be instituted. Discontinue the corticosteroid if a favorable response does not occur promptly, until the infection has been adequately controlled.
The following local adverse reactions (in order of decreasing frequency) are reported infrequently with topical corticosteroids (but may occur more frequently with occlusive dressings): burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, miliaria.